Locally Applied Agents

Long Lasting Gum Disease Treatments

As an adjunct to mechanical dental cleaning, Dr. Culberson may recommend the use of locally-applied agents. These substances are placed into the pockets between the tooth and the gum and may be an antibiotic or an anti-inflammatory agent. They typically start working quickly, right at the source of infection, and keeps fighting bacteria long after you leave the dental office.

Studies indicate that some agents are effective for 30 days,2 after the dental cleaning and may provide significantly better results than scaling and root planing alone for up to 90 days.3

1. Oringer RJ, Al-Shammari KF, Aldredge WA, et al. Effect of locally administered minocycline microspheres on markers of bone resorption. J Periodontol 2002;73:835-842.
2. Goodson JM, Gunsollwy JC, Grossi SG, et al. Minocycline HCl microspheres reduce red-complex bacteria in periodontal disease therapy. J Periodontol 2007;78(8):1568-1579.
3. Williams RC, Paquette DW, Offenbacher S, et al. Treatment of periodontitis by local administration of minocycline microspheres: a controlled trial. J Periodontol 2001;72:1535-1544.